Heres a few transaction scenarios for you, you can also check out the walgreens thread for more great ideas.

I try and arrange these Transactions so as to spend as little cash out of pocket as possible. That explains why there are sometimes several single order transactions and sometime I list just a couple of multiple order transactions.

Transaction #1
Buy: 1x Colgate Total Advanced Toothpaste 5.8oz. $3.49
Use: 1x Colgate Total Advanced Whitening, Total Enamel Strength, Total Advanced Clean or Total Advanced Fresh, 4.0oz. or larger $1/1 (7-31-10) SS-7/11
Pay: $2.49
Get: $3.50 Register Reward

Transaction #2
Buy: Gillette Fusion Pro Glide Manual or Power Razor System $9.89
Use: Gillette Fusion Razor, any $4/1 (7-31-10) PG-6/6
Use Register Rewards: $3.50 from Transaction #1
Pay: $2.39
Get: $5 Register Reward

Transaction #3
Buy: 1x Dr. Scholls Massaging Gel Insoles $11.99 (price online)
1x Pilot G2 Pens, 2 pack $1.19
Use Manufacturer Coupons:
1x $2/1 Dr. Scholls Massaging Gel Insoles: Printable Coupon- https://www.drscholls.com/drscholls/company/specialoffers.jsp
1x $1/1 Pilot Pens: Printable Coupon- https://www.notjustapen.com/Registration (the cashier will probably adjust this down to $0.19 to avoid an overage)
Use Store Coupons:
1x $1/1 Pilot Pens Instant Store Coupons
Use Register Rewards: $5.00 From Transaction #2
Pay: $4.99
Get: $5 Register Reward

In the end you pay $7.89 out of pocket and leave with a $5 register reward. Adjusted total after register rewards is $2.89 for 5 pkg Keebler crackers, 2pkg Twizzlers and a nice Gillette Razor!

Back to School Deals
Penway Wooden Ruler, 12in. $0.09
Penway 2 Pocket Folder $0.09
Penway Highlighter $0.09
Penway Notebook 60 or 70 sheets $0.29
Penway Pink Erasers, 2 pack $0.29
Corner Office Sheet Protectors, 10 pack $0.29
Penway Glue Sticks 3 pack, Jumbo Glue Stick or Glue 4oz. $0.49
Splash Poly Portfolio $0.49
School Box $0.49
Bic Brite Liner Highlighters $0.49
Print Works Multipurpose Paper, 400 sheets Limit 2. $1.99
Pilot G2 Pens, 2 pack $0.19 (After instant coupon in stores)
Penway Fabric Carry All Case $0.99
Penway 10 pack Classic Markers $0.99
Dixon 25 pack Variety Pencil Set $0.99
Crazerasers 4 pack $0.99
Corner Office 5 tab Dividers $0.39
Penway 15 pack Cap Erasers $0.39
Penway Poly or 3 ring Binder $0.39
Sharpie Markers or Pens 2 to 4 pack pens, 8 pack markers $3.99
Notebook 5 subject, 180 sheets, wide or College ruled $1.99
Expo Washable Markers, 6pack $2.99 (After instant coupon in stores)
Crayola Crayons 24 pack, Limit 3 $0.79 (Requires in Ad Store Coupons)
Penway Filler Paper, 280 sheets, wide or college ruled. Limit 3 $1.49 (Requires in Ad Store Coupons)

Questions about how Register Rewards work? Go here for the answers.